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KMID : 0361020120550090565
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Korean Journal of Otolaryngology - Head and Neck Surgery
2012 Volume.55 No. 9 p.565 ~ p.570
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Comparative Study of Preoperative Imaging Detection and Localization Test for Hyperparathyroidism
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Sung Eui-Suk
Ji Seon-Yeong
Choi Yoon-Young
Kim Ji-Young
Park Jeong-Seon
Lee Young-Jun
Tae Kyung
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Abstract
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Background and Objectives : Accurate preoperative localization of abnormal parathyroid gland is essential for successful parathyroidectomy. The aim of this study was to evaluate the accuracy of a localization test for hyperparathyroidism including ultrasonography (US), computed tomography (CT) and 99mTc-sestamibi scan.
Subjects and Method: We studied 47 patients with hyperparathyroidism who underwent parathyroidectomy from January 2003 through December 2010, retrospectively. 99mTc-sestamibi scan, US and CT were carried out as a preoperative localization test and their accuracy were analyzed according to the size, location and pathology of parathyroid lesions.
Results: The accuracy of 99mTc-sestamibi scan, US and CT were 93%, 77% and 65%, respectively. The accuracy of 99mTc-sestamibi scan and CT combined was 94% and US and CT 73%. The accuracy of combination of US and 99mTc-sestamibi scan was 96%, which was not different depending on size, location and pathology of parathyroid lesions.
Conclusion: The combination of 99mTc-sestamibi scan and US is the most effective method for preoperative detection and the localization of hyperparathyroidism.
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KEYWORD
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Hyperparathyroidism, Localization, Parathyroidectomy, Ultrasonography, 99mTc-sestamibi scan
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